PhD thesis in Biomedical and Pharmaceutical Sciences

Bruxelles Woluwe

April 28, 2017

Owein Guillemot-Legris

(Bioanalysis and Pharmacology of Bioactive Lipids, LDRI) / promotor: Pr Giulio Muccioli

Central nervous system neuroinflammation in the context of obesity: implications of bioactive lipids and pathophysiological repercussions

related publications:

° Guillemot-Legris O*, Mutemberezi V.*, et al. Obesity is associated with changes in oxysterol metabolism and levels in mice liver, hypothalamus, adipose tissue and plasma. Sci Rep. 2016, 6:19694.

° Guillemot-Legris O et al., High-fat diet feeding differentially affects the development of inflammation in the central nervous system. J Neuroinflammation. 2016, 13(1):206

° Guillemot-Legris O et al., Oxysterols in Metabolic Syndrome: From Bystander Molecules to Bioactive Lipids. Trends Mol Med. 2016, 22(7):594-614

° Guillemot-Legris O et al., Obesity-Induced Neuroinflammation: Beyond the Hypothalamus. Trends Neurosci. 2017, 40(4):237-253