LDRI Seminar

Bruxelles Woluwe

October 09, 2017

Monday 9 October 2017, 13h, Salle Couvreur (Mounier avenue 73/0)

Prof. Pascal Kienlen Campard

Institute of Neurosciences

Folding of APP membrane regions: the shape of Alzheimer's disease to come?

Related publications

  • Decock et al (2016) Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Abeta Oligomers in Cells. Front Aging Neurosci 8:107.
  • Decock et al. (2015) Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing. FEBS Open Bio 5:763-773.
  • Tang et al. (2014) Conformational Changes Induced by the A21G Flemish Mutation in the Amyloid Precursor Protein Lead to Increased Abeta Production. Structure 22:387-396.

Info: F. Van Bambeke, françoise.vanbambeke@uclouvain.be