Publications
LIBST
Publications
2018
Desguin, Benoît ; Fellner, Matthias ; Riant, Olivier ; Hu, Jian ; Hausinger, Robert ; Hols, Pascal ; Soumillion, Patrice. Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.. In: Journal of Biological Chemistry, (2018). doi:10.1074/jbc.RA118.003741.
2018
Crowet, Jean Marc ; Nasir, Mehmet Nail ; Dony, Nicolas ; Deschamps, Antoine ; Stroobant, Vincent ; Morsomme, Pierre ; Deleu, Magali ; Soumillion, Patrice ; Lins, Laurence. Insight into the Self-Assembling Properties of Peptergents: A Molecular Dynamics Simulation Study.. In: International Journal of Molecular Sciences (Print), Vol. 19, no.9, p. 2772 (2018). doi:10.3390/ijms19092772.
2017
van den Biggelaar, Ludivine ; Soumillion, Patrice ; Debecker, Damien P.. Enantioselective Transamination in Continuous Flow Mode with Transaminase Immobilized in a Macrocellular Silica Monolith. In: Catalysts, Vol. 7, no.54, p. 1-13 (2017). doi:10.3390/catal7020054.
2017
Galka, Pierre ; Jamez, Elisabeth ; Joachim, Gilles ; Soumillion, Patrice. QuickLib, a method for building fully synthetic plasmid libraries by seamless cloning of degenerate oligonucleotides.. In: PLoS One, Vol. 12, no.4, p. e0175146 (2017). doi:10.1371/journal.pone.0175146.
2017
Desguin, Benoît ; Soumillion, Patrice ; Hausinger, Robert P. ; Hols, Pascal. Unexpected complexity in the lactate racemization system of lactic acid bacteria. In: FEMS Microbiology Reviews, Vol. 41, no. Supp_1, p. S71-S83 (2017 Aug 1). doi:10.1093/femsre/fux021.
2016
Desguin, Benoît ; Soumillion, Patrice ; Hols, Pascal ; Hausinger, Robert P. Nickel-pincer cofactor biosynthesis involves LarB-catalyzed pyridinium carboxylation and LarE-dependent sacrificial sulfur insertion.. In: Proceedings of the National academy of sciences of the United States of America, Vol. 113, no.20, p. 5598-5603 (2016). doi:10.1073/pnas.1600486113.
2015
Desguin, Benoît ; Zhang, Tuo ; Soumillion, Patrice ; Hols, Pascal ; Hu, Jian ; Hausinger, Robert P. A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase.. In: Science, Vol. 349, no.6243, p. 66-69 (2015). doi:10.1126/science.aab2272.
2015
Woronoff, Gabrielle ; Ryckelynck, Michaël ; Wessel, Julia ; Schicke, Olivier ; Griffiths, Andrew D ; Soumillion, Patrice. Activity-Fed Translation (AFT) Assay: A New High-Throughput Screening Strategy for Enzymes in Droplets.. In: ChemBioChem : a European journal of chemical biology, Vol. 16, no. 9, p. 1343-1349 (2015). doi:10.1002/cbic.201500087.
2015
Proost, Joris ; Deschuyteneer, Geneviève ; Santoro, Ronny ; Van Overmeere, Quentin ; Soumillion, Patrice ; Flandre, Denis. Filamentous Phages Displaying Multivalent Peptide Motives With Specific Affinity To Anodic Alumina Surfaces. In: Journal of Biosensors & Bioelectronics, Vol. 6, no. 1, p. 1000162 (2015). doi:10.4172/2155-6210.1000162.
2014
Vorobieva, Anastassia A ; Khan, Mohammad Shahneawz ; Soumillion, Patrice. Escherichia coli D-malate dehydrogenase, a generalist enzyme active in the leucine biosynthesis pathway.. In: Journal of Biological Chemistry, Vol. 289, no.42, p. 29086-29096 (2014). doi:10.1074/jbc.M114.595363.
2014
Desguin, Benoît ; Goffin, Philippe ; Viaene, Eric ; Kleerebezem, Michiel ; Martin-Diaconescu, Vlad ; Maroney, Michael J ; Declercq, Jean-Paul ; Soumillion, Patrice ; Hols, Pascal. Lactate racemase is a nickel-dependent enzyme activated by a widespread maturation system.. In: Nature Communications, Vol. 5, p. 3615 (2014). doi:10.1038/ncomms4615.
2013
Alsteens, David ; Trabelsi, Heykel ; Soumillion, Patrice ; Dufrêne, Yves. Multiparametric atomic force microscopy imaging of single bacteriophages extruding from living bacteria. In: Nature Communications, Vol. 4, p. 1-7 (2013). doi:10.1038/ncomms3926.
2012
Ponsard, Isabelle ; Soumillion, Patrice. New immunoenzymatic strategy for rapid and selective growth of salmonella.. In: Journal of clinical microbiology, Vol. 50, p. 4138-40 (2012). doi:10.1128/JCM.01765-12.
2011
Volkov, Alexander N ; Barrios, Humberto ; Mathonet, Pascale ; Evrard, Christine ; Ubbink, Marcellus ; Declercq, Jean-Paul ; Soumillion, Patrice ; Fastrez, Jacques. Engineering an allosteric binding site for aminoglycosides into TEM1-β-Lactamase.. In: ChemBioChem : a European journal of chemical biology, Vol. 12, no. 6, p. 904-13 (2011). doi:10.1002/cbic.201000568.
2011
Woronoff, Gabrielle ; El Harrak, Abdeslam ; Mayot, Estelle ; Schicke, Olivier ; Miller, Oliver J ; Soumillion, Patrice ; Griffiths, Andrew D ; Ryckelynck, Michael. New generation of amino coumarin methyl sulfonate-based fluorogenic substrates for amidase assays in droplet-based microfluidic applications.. In: Analytical Chemistry, Vol. 83, no. 8, p. 2852-2857 (2011). doi:10.1021/ac200373n.
2010
Shi, Yi-Feng ; Soumillion, Patrice ; Ueda, Mitsuyoshi. Effects of catalytic site mutations on active expression of phage fused penicillin acylase. In: Journal of Biotechnology, Vol. 145, no. 2, p. 139-142 (2010). doi:10.1016/j.jbiotec.2009.11.009.
2010
Mathieu, Valéry ; Fastrez, Jacques ; Soumillion, Patrice. Engineering allosteric regulation into the hinge region of a circularly permuted TEM-1 {beta}-lactamase.. In: Protein engineering, design & selection : PEDS, Vol. 23, no. 9, p. 699-709 (2010). doi:10.1093/protein/gzq041.
2010
Deschuyteneer, Geneviève ; Garcia, Stephanie ; Michiels, Benjamin ; Baudoux, Bruno ; Degand, Hervé ; Morsomme, Pierre ; Soumillion, Patrice. Intein-Mediated Cyclization of Randomized Peptides in the Periplasm of Escherichia coli and Their Extracellular Secretion. In: ACS Chemical Biology, Vol. 5, no. 7, p. 691-700 (2010). doi:10.1021/cb100072u.
2017
Desguin, Benoît ; Soumillion, Patrice ; Hols, Pascal ; Hu, Jian ; Hausinger, Robert P.. Lactate Racemase and Its Niacin-Derived, Covalently-Tethered, Nickel Cofactor. In: Deborah Zamble, Magdalena Rowińska-Żyrek, Henryk Kozłowski, The Biological Chemistry of Nickel (Metallobiology Series; 10), The Royal Society of Chemistry, 2017. 978-1-78262-498-1. doi:10.1039/9781788010580.
2018
Debecker, Damien P. ; van den Biggelaar, Ludivine ; Gauchet, Adrien ; Khan, Mohammad Shahneawz ; Soumillion, Patrice. Immobilizing transaminase in a macroporous silica monolith for flow mode enantioselective transamination . International Symposium on Relations between Homogeneous and Heterogeneous Catalysis (ISHHC18) (Sydney, Australia, du 22/07/2018 au 25/07/2018).
2017
van den Biggelaar, Ludivine ; Soumillion, Patrice ; Debecker, Damien P.. Hybrid NH2-silica monolith as support for biocatalysis in flow: leveraging on a better control of the aminopropyl dispersion. 19th International Sol-Gel Conference (Liège, Belgium,, du 03/09/2017 au 08/09/2017).
2016
van den Biggelaar, Ludivine ; Soumillion, Patrice ; Debecker, Damien P.. Biocatalytic transaminations in continuous Flow. FineCat 2016 (Palermo, du 06/04/2016 au 07/04/2016).
2014
Soumillion, Patrice. Accelerated evolution of enzymes: traps, hurdles and secret passages. Adebiotech – Enzymes Innovations Industries (Paris, du 27/10/2014 au 28/10/2014).
2014
Wessel, Julia. Directed ecvolution of a beta-lactamase using microfluidics. The 16th EMBL PhD Symposium: Inspired by Biology - Exploring Nature's Toolbox (Heidelberg, du 23/10/2014 au 25/10/2014).
2014
Box, Olivier. Directed evolution of an enzyme from a chromosomal gene. The 16th EMBL PhD Symposium: Inspired by Biology - Exploring Nature's Toolbox (Heidelberg, du 23/10/2014 au 25/10/2014).
2014
Soumillion, Patrice. Neutralization of an Enzyme Promotes its Neofunctionalization. 4th International Conference on Novel Enzymes (Ghent, du 14/10/2014 au 17/10/2014).
2012
Soumillion, Patrice. New Enzyme Screening Strategy for Droplet-Based Microfluidic Applications. Protein Engineering for Biocatalysis (Greifswald, Germany, du 29/08/2012 au 31/08/2012).
2011
Soumillion, Patrice. Engineering allosteric beta-lactamases by phage display. ArtZymes (Marseilles, du 25/09/2011 au 28/09/2011).
2010
Trabelsi, Heykel ; Soumillion, Patrice. Directed evolution of a DD-Peptidase into a Beta-lactamase. 35th Congress of the Federation-of-European-Biochemical-Societies (Gothenburg (Sweden), Jun 26-jul 01, 2010). In: The F E B S Journal, Vol. 277, p. 302-302 (2010).
2010
Baudoux, B. ; Soumillion, Patrice. Genetic engineering of allosteric beta-lactamases. 35th FEBS Congress (Gothenburg, Sweden, du 26/06/2010 au 01/07/2010). In: The F E B S Journal, Vol. 277, p. 250-250 (2010). doi:10.1111/j.1742-4658.2010.07680.x.
2010
Mercier, Dimitri ; Tang, Xiaohui ; Santoro, Ronny ; Sbille, Isabelle ; Codina, A. ; Moreno, L. ; Soumillion, Patrice ; Flandre, Denis ; Proost, Joris. Integrated capacitive biosensors based on filamentous phages. 20th World Congress on Biosensors (Glasgow (Scotland), du 26/05/2010 au 28/05/2010). In: Proceedings of the 20th World Congress on Biosensors, 2010, p. P2.1.093.
2011
Soumillion, Patrice ; Baudoux, Bruno. Method for extracellular production of recombinant biomolecules in a microorganism. Numéro de priorité ; Déposé ; Publié (2011-11-17). WO WO.
2010
Proost, Joris ; Santoro, Ronny ; Soumillion, Patrice ; Flandre, Denis ; Deschuyteneer, Geneviève. Genetically modified bacteriophage, biosensor containing same, and method of use. Numéro de priorité ; Déposé ; Publié (2010-12-16). N/A N/A.
Provided by DIAL