Ruben Martherus, Postdoc fellow

Post-doctoral fellow (2014- )

PhD molecular cardiovascular biology, Maastricht University (Maastricht, The Netherlands 2011)
M.Sc. Biotechnology, Wageningen University (Wageningen, The Netherlands, 2002)
B.Sc. Biotechnology, Hogeschool van Amsterdam (Amsterdam, The Netherlands, 2000

Professionnal experience

2010-2013: Postdoctoral Research Fellow
Cincinnati Children’s Hospital Medical Center (Cincinnati, OH USA)
- Identification of cardiac disease causing genetic variants by
Next Generation Sequencing and Sanger sequencing
- Study mechanisms involved in cardiac disease in in vitro and mouse in vivo models.
- Creation of new mouse models

2002-2003: Researcher
Wuhan Institute of Virology, Chinese Academy of Sciences (Wuhan, P.R. China)
-    Molecular virology of invertebrate viruses.

Function/Job description

Validation of a gene expression signature for prognostic value in breast cancer.
Identify mechanisms of cancer cells adaptation to acidosis.
Providing technical / scientific support in relation to molecular biology and especially gene expression analysis for the various lab-groups.

Skills highlights

Molecular Cell Biology
Molecular virology
Regulation of gene expression
Transcriptomics
Next Generation Sequencing
Cardiovascular biology