Spyridon Agathos

Fundamental and applied research and development in: Biotechnology for Sustainability; Biochemical
Engineering; Applied and Environmental Microbiology; Enzyme Stability; Bacterial, Fungal,
Algal, Insect and Mammalian Cell Cultures in Bioreactors; Cell and Enzyme Immobilization for Biocatalysis;
Pollutant Biodegradation and Site Bioremediation

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Ph.D. Theses Supervised and Completed:

Rutgers

University

 1.       

J. Lee, Ph.D. in Chemical & Biochemical Enginering, August 1989, Physiological Factors in Cyclosporin A Production by Tolypocladium inflatum

- Experimental and Mathematical Modeling

2.     G.-T. Chun, Ph.D. in Chemical & Biochemical Enginering, January 1992, Comparative Bioreactor Studies of Suspended and

Immobilized Cell Systems for Optimal Production of Cyclosporin A

3.        

E.K.
Hong, Ph.D., January 1992, Plasmid Propagation and Heterologous Gene
Expression in Recombinant Yeast (Co-supervisor: A. Constantinides)

4.        

W. Hensler, Ph.D., January 1994, Growth, Infectivity, and Recombinant Protein Expression in Insect Cell Culture

Catholic

University of Louvain

5.        

S.
El Fantroussi, Doctorate in Applied Natural Sciences, May 1997,
Introduction of Anaerobic Bioremediation Activities in Soil: From
Laboratory Bench Scale to Pilot Soil Bioreactor (Co-supervisor: H.
Naveau)

6.        

C.M. Peres, Ph.D.
, November 1998,
Improved Biodegradation of Nitroaromatic Compounds: Degradation of a
Nitroaromatic Compound together with the Aminoaromatic Derivative
Produced by its Reduction

7.       

V.A.
Acha  Fuertes, Ph.D.,
June 1999, Development of a FTIR Sensor for Monitoring and Modelling an
Anaerobic Dechlorinating Bioreactor (Co-supervisor: H. Naveau)

8.        

S. Goux
, Ph.D., March 2000,
Biodegradation of Atrazine by Soil Microorganisms: Molecular Aspects and
Potential Use in Bioremediation (Co-supervisor: L. Pussemier)

9.       

B. Van Aken, 
Ph.D.,

November 2000, Biodegradation of 2;4;6-Trinitrotoluene (TNT) by White-Rot Fungi

10.        

L. Coulibaly, Ph.D.,
January 2002, Bioconversion de macromolécules dans un réacteur simulant
un écoulement piston en régime transitoire : cas de la bioremédiation
d'eaux usées synthétiques par Aspergillus niger



11.      

L.
Ikonomou, Doctorate in Applied Sciences, June 2002, Development of High
Density Systems for the Production of Recombinant Proteins by Insect
Cells

(Co-supervisor: G. Bastin).

12.    

J. Mols, Doctorate in Sciences, July 2004. 

Cultivation
of Chinese Hamster Ovary (CHO) Cells in Protein-Free Media Supplemented
with Plant Peptones is Sufficient to Prevent Proteolysis of Secreted
Rcombinant Glycoproteins (Co-supervisor: Y.-J. Schneider)

13.        

J. Dries, Ph.D., September 2004. 

Development and Comparison

of
Different Multiple Permeable Reactive Barrier (MPRB) Concepts for the
Treatment of Groundwater Contaminated by Pollutant Mixtures (Co-supervisor:

L. Bastiaens).

14.        

L. Eyers,
Ph.D., January 2007. Characterization of Bacterial Populations of 2,4,6-Trinitrotoluene (TNT) Contaminated Soils and Isolation of a Pseudomonas aeruginosa

Strain with TNT Denitration Activities.

15.         

J.-C. Drugmand,
Ph.D.,
February 2007. Characterization of Insect Cell Lines Is Required for
Appropriate Industrial Processes: Case Study of High-Five Cells for
Recombinant Protein Production.

16.        

L.
Schuler, Doctorate in Exact Sciences, December 2007. Identification of
Genes Involved in the Degradation of Polycyclic Aromatic Hydrocarbons by
Two Sphingomonas

spp.

17.        

H.
Cabana, Joint doctorate in Agronomical Sciences and Bioengineering
(Catholic University of Louvain) and in Applied Sciences --
specialization Chemical Engineering (University of Sherbrooke, Québec,
Canada), April 2008. Elimination of the endocrine disruptors
nonylphenol, bisphenol A and triclosan by the oxidative action of the
laccase from Coriolopsis polyzona

.

18.      

Benoît Stenuit, Ph.D., November 2009. Biological degradation of 2,4,6 – Trinitrotoluene (TNT): Bioprospecting
for TNT-denitrating bacteria and deciphering of multiple TNT denitration
pathways.

19.       Jean-François Michiels,
Ph.D., May 2011. “Investigation of the role of peptones in
animal cell culture: Case study of a commercial soy peptone in a CHO cell
serum-free medium” (Co-supervisor: Y.-J. Schneider).

20.     Sébastien Sart, Ph.D., August 2011. "Controlled expansion and differentiation of mesenchymal stem cells in microcarrier-based stirred bioreactors" (Co-supervisor: Y.-J. Schneider).